Tiatrex provides synergistic activity of tiamulin and chlortetratcycline (CTC) towards the control of diseases in poultry. The synergistic activity is due to their similar mode of action on the ribosome, the site where proteins are produced.
It is ideal for the combat of mycoplasma and bacterial infections as well as bringing about an improvement in feed conversion and egg protection.
Tiatrex can provide synergistic response many times greater than other antibiotic combinations. Tiamulin is very well absorbed from the gut of chickens (over 90%) and reached peak levels in blood within 2 to 4 hours. It also has the ability to concentrate in lung tissue (up to 40 times higher) making it particularly effective against respiratory infections. CTC’s high gut concentration on the other hand, helps reduce enterobacterial infections and contaminations.
Tiatrex can be used in the prevention and treatment of Chronic Respiratory Disease (CRD), Complicated Chronic Respiratory Disease (CCRD), Infectious Bursal Disease (IBD), Infectious Coryza and Fowl Cholera.
Dosage and Administration:
Species / Dosage at 21OC / Dosage at 32OC
Breeder (17 weeks and above) / Mix 100 g per 50 L drinking water. / Treatment: Mix 100 g per 100 L drinking water.
Layers (17 weeks and above) / Mix 100 g per 50 L drinking water. / Treatment: Mix 100 g per 100 L drinking water.
Chick Broiler (prevention) Mix 100 g per 50 L drinking water. / Mix 100 g per 100 L drinking water.
For general use:
growth promotion and egg production / Mix 100 g per 200 L drinking water. / Mix 100 g per 400 L drinking water.
Tiatrex has contraindications with ionophore anticoccidials such as Monensin, Salinomycin and Narasin. These are incompatible with Tiatrex when used in drinking water at prevention and treatment levels of 0.0125% an 0.025%, respectively. The signs of interaction are feed and water intake depression, growth depression, paralysis and in severe case, death. The safety margins of the incompatible ionophores are fairly narrow. It is thought that the interaction is caused by interference of the metabolism and excretion of the ionophores resulting in an overdose effect. This interaction is dose dependent and Tiatrex at 40-50 ppm did not cause signs when fed with 100 ppm monensin, 60ppm salinomycin and 60 ppm narasin. Levels above 50 ppm may start to cause signs of interaction.
Store in cool and dry place. Avoid direct heat and sunlight. Keep the bag tightly closed and out of reach of children.
100 g, 500 g and 1 Kg