Tilvalozag 250 WSP is a macrolide antibiotic that has antibacterial activity against Gram-positive, some Gram-negative organisms and mycoplasma.

It acts by inhibiting protein synthesis in the bacteria cell. Macrolide antibiotics are the metabolites or semi-synthetic derivatives of metabolites of soil organisms obtained by fermentation.

Tilvalozag 250 WSD interfere with protein synthesis by reversibly binding to the 50S ribosome subunit. They bind to the donor site and prevent the translocation necessary for keeping the peptide chain growing. Tylvalozag 250 WSD is generally considered bacteriostatic and mycoplasmastatic.

Composition Tylvalosin (as Tylvalosin tartrate)...... 250 g/kg Indications Chickens - For treatment of respiratory infections caused by Mycoplasma gallisepticum. - For treatment of diseases associated with to Clostridium perfringens Turkeys - For treatment of respiratory disease associated with tylvalosin sensitive strains of Ornithobacterium rhinotracheale.

Pigs - For treatment of swine enzootic pneumonia caused by Mycoplasma hyopneumoniae, porcine proliferative enteropathy caused by the intracellular bacterium Lawsonia intracellularis, swine dysentery caused by Brachyspira hyodysenteria, and colitis caused by Brachyspira pilosiqali.

Dosage and administration Chicken - For treatment of respiratory disease associated with Mycoplasma gallisepticum: 25 mg tylvalosin per kg bodyweight per day in drinking water for 3 consecutive days. - For treatment of diseases associated with Clostridium perfringens: 25 mg tylvalosin per kg bodyweight per day in drinking water for 4 consecutive days.

Turkeys - For treatment of respiratory disease associated with Ornithobacterium rhinotracheale: 25 mg tylvalosin per kg bodyweight per day in drinking water for 5 consecutive days.

Pigs - For treatment of swine enzootic pneumonia caused by Mycoplasma hyopneumoniae, porcine proliferative enteropathy caused by the intracellular bacterium Lawsonia intracellularis, swine dysentery caused by Brachyspira hyodysenteria, and colitis caused by Brachyspira pilosiqali: 5 mg tylvalosin per kg bodyweight per day in drinking water for 5 consecutive days. Withdrawal period - Meat and offal: 2 days. Eggs (chicken): zero days.

Turkeys: do not use within 21 days of the onset of lay. - Not authorised for use in turkeys producing eggs for human consumption. Storage Store in a cool and dry place. Avoid direct heat and sunlight.

Packing Tilvalozag 250 WSP is packed in 100 g, 500 g and 1 kg sachets.